Ewan Goligher MD PhD is Associate Professor of Medicine and Physiology and Arrell Chair of Precision Critical Care Medicine at the University of Toronto and the Keenan Centre for Biomedical Research, St. Michael's Hospital, Toronto, Canada. He co-chairs the PRACTICAL platform trial, investigating therapies for acute hypoxemic respiratory failure and sepsis. As a critical care physician and clinical trialist, he is interested in ethical issues at the nexus of end of life care and research involving emergency interventions in incapacitated patients.